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The following Python program runs in 55ms.

Solution:PUZZLE = 102235.Here’s a solution using the general Alphametic solver [[

`SubstitutedExpression()`

]] from theenigma.pylibrary. We introduce new (lower case) symbols that are not required to be distinct from the other symbols to represent the multiplicands of the sum.The whole thing runs in 111ms. Here is the command and its output: